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用美国US Biomax生产的组织芯片,微组织阵列发表的部分参考文献

    Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
    CM Rudin, S Durinck, EW Stawiski, JT Poirier, … — Nat. Genet., 2012
    … microarrays. SCLC tissue microarrays were obtained from US Biomax (LC703, LC802a, LC1009 and LC10010a) for IHC and FISH as fresh-cut slides. The four …
    Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion
    G Wang, A Lunardi, J Zhang, Z Chen, … — Nat. Genet., 2013
    … at the Memorial Sloan-Kettering Cancer Center (MSKCC) or purchased from US Biomax, Inc., and stained in Pathology and Molecular Cytology Core Facilities …
    Frequent truncating mutations of STAG2 in bladder cancer
    DA Solomon, JS Kim, J Bondaruk, SF Shariat, … — Nat. Genet., 2013
    … spotted in triplicate, (ii) ovarian cancer tumor microarray OV1921 from US Biomax containing …
    Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma
    CS Lee, A Bhaduri, A Mah, WL Johnson, … — Nat. Genet., 2014
    … Each SCC used for allelic discrimination contained ≥80% tumor tissue (US Biomax). Genomic DNA was isolated from all specimens using the DNeasy Blood and …
    GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer
    KL Scott, O Kabbarah, MC Liang, E Ivanova, … — Nature, 2009
    PA802 pancreatic carcinoma and ME1001 melanoma tissue microarrays were from US Biomax. FISH was prepared following standard protocols. BAC RP11-437P15 was …
    Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
    AD Boiko, OV Razorenova, M van de Rijn, SM Swetter, … — Nature, 2010
    … upon intradermal injection in Paraffin melanoma tissue array slides (US Biomax Inc.) containing 80 1.5-mm tissue cores from primary and metastatic …
    TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
    X Su, D Chakravarti, MS Cho, L Liu, … — Nature, 2010
    … carcinomas (LC1005) and mammary adenocarcinomas (BR480) were obtained from US …
    Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
    M Jaskelioff, FL Muller, JH Paik, E Thomas, … — Nature, 2011
    … determine telomerase activity with a Quantitative Telomerase Detection kit (US Biomax) following the manufacturer’s recommendations. 0.5 μg total protein …
    The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
    CJ Ceol, Y Houvras, J Jane-Valbuena, S Bilodeau, … — Nature, 2011
    … green counterstain was used. Melanoma tissue microarrays were obtained from US Biomax (ME1003 and ME482). A modified visual semiquantitative method was used …
    Suppression of lung adenocarcinoma progression by Nkx2-1
    MM Winslow, TL Dayton, RG Verhaak, C Kim-Kiselak, … — Nature, 2011
    … and HMGA2 in human lung adenocarcinoma we stained a tissue microarray (US BioMax, LC1921) for these proteins using the antibodies described above. …
    Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
    R Straussman, T Morikawa, K Shee, M Barzily-Rokni, … — Nature, 2012
    … normal skin, naevi and melanomas (ME1004a and ME803a) were purchased from US Biomax. Colorectal cancer TMAs were prepared as described …
    USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110
    J Li, V D'Angiolella, ES Seeley, S Kim, … — Nature, 2013
    … 4 . Tissue microarray. Pancreatic tissue arrays were purchased from US Biomax (PA1001 and PA207). Immunohistochemical staining was performed as …
    RNAi screens in mice identify physiological regulators of oncogenic growth
    S Beronja, P Janki, E Heller, WH Lien, … — Nature, 2013
    … Skin squamous cell cancer tissue array (SK802a) was obtained from US Biomax Inc. Immunohistochemistry preparations were developed using ImmPRESS …
    PVT1 dependence in cancer with MYC copy-number increase
    YY Tseng, BS Moriarity, W Gong, R Akiyama, … — Nature, 2014
    … multiple organ tumour tissue microarray slides (BC00119) were obtained from US Biomax. In situ hybridization used digoxigenin-labelled PVT134 probe according …
    Fructose-1,6-bisphosphatase opposes renal carcinoma progression
    B Li, B Qiu, DS Lee, ZE Walton, … — Nature, 2014
    … microarray slides (KD801, KD208, BC07114, BC07115, LV804, and LV208 from US Biomax) were deparaffinized by baking slides at 60 °C for 30 min. The slides …
    A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion
    M Overholtzer, AA Mailleux, G Mouneimne, G Normand, … — Cell, 2007
    … cleaved caspase-3 staining. Human tumor tissue arrays were purchased from US …
    USP10 regulates p53 localization and stability by deubiquitinating p53
    J Yuan, K Luo, L Zhang, JC Cheville, … — Cell, 2010
    … Microarray The tissue arrays of Kidney cancer samples were purchased from US Biomax (KD 2083, KD991t, KD804, KD241, and KD208t). Immunohistochemical …
    Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
    CG Lian, Y Xu, C Ceol, F Wu, … — Cell, 2012
    … other TMA (ARY, US Biomax, inc.) contained 79 evaluable specimens including 27 primary melanomas and 27 melanoma metastases. …
    Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
    L Cheng, Z Huang, W Zhou, Q Wu, … — Cell, 2013
    … Sections of GBM specimens or tissue arrays (Duke Brain Tumor Center and US Biomax) were immunostained for a-SMA to mark pericytes or CD31 to label ECs, …
    Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion
    L Li, D Hanahan, , — Cell, 2013
    … microarrays were purchased from US Biomax http://www.biomax.us/ (Pancreatic cancer: PA481. Ovarian cancer: OV241a. Breast cancer: BCA961. Glioma: …
    PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells
    WJ Israelsen, TL Dayton, SM Davidson, BP Fiske, … — Cell, 2013
    … in human breast cancers was analyzed in three tissue microarrays: US BioMax BR1504, one multitissue TMA-containing tissue from the archives of the …
    Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors
    BM Emerling, JB Hurov, G Poulogiannis, KS Tsukazawa, … — Cell, 2013
    … we show that a subset of breast cancers express high levels of the type 2 phosphatidylinositol-5-phosphate 4-kinases α and/or β (PI5P4Kα and β) and …
    Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation
    N Pencheva, CG Buss, J Posada, T Merghoub, … — Cell, 2014
    … blinded immunohistochemical analyses of cutaneous melanoma lesions from the US Biomax TMA (K C) into mice that were administered a normal chow or a chow …
    Programmed translational readthrough generates antiangiogenic VEGF-Ax
    SM Eswarappa, AA Potdar, WJ Koch, Y Fan, … — Cell, 2014
    … arrays contained 1.5-mm by 5-mm thick samples (US Biomax). The adenocarcinoma array contained samples from 30 cases and 5 healthy individuals. Sections …
    Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin
    A Chandrasekaran, A Srinivasan, R Raman, K Viswanathan, … — Nat. Biotechnol., 2008
    … interacting with a long 2-6 Normal human trachea (US Biological) and lung (US Biomax) tissue sections were deparaffinized, rehydrated and incubated with 1% …
    Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect
    M Milyavsky, I Shats, A Cholostoy, R Brosh, … — Cancer Cell, 2007
    … in situ hybridization using the Soft Tissue Cancer tissue array (SO801, US Biomax), and detection of myocardin and vimentin using cancer profiling array …
    Loss of TGFbeta signaling destabilizes homeostasis and promotes squamous cell carcinomas in stratified epithelia
    G Guasch, M Schober, HA Pasolli, EB Conn, … — Cancer Cell, 2007
    … and 41 female genital SQCCs (UV241, UV801, PE241, PE801) were obtained from US Biomax, Rockeville, MD. Paraffin slides were deparaffinized and stained with …
    Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
    RH Wang, K Sengupta, C Li, HS Kim, … — Cancer Cell, 2008
    … antibodies. The tissue array of breast cancer samples was purchased from US Biomax (Cat. BR1002). Immunohistochemical staining against SIRT1 (Cat. 07-131, …
    Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression
    JA Reuter, S Ortiz-Urda, M Kretz, J Garcia, … — Cancer Cell, 2009
    … For tissue microarrays, nonoverlapping skin SCC arrays (SK801 and SK802; US Biomax) and a panel of SCC in situ patient samples were deparaffinized, …
    Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment
    DA Chan, TL Kawahara, PD Sutphin, HY Chang, … — Cancer Cell, 2009
    … hypoxia treatment. Colon and breast tissue microarrays were purchased from US Biomax. All human tissues for the tissue microarrays were obtained with …
    Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate
    L Wang, R Liu, W Li, C Chen, … — Cancer Cell, 2009
    … information. Tissue microarray samples came from the University of Michigan, Biomax (US Biomax, Inc., Rockville, MD), and Target Biotech (Target Biotech, …
    miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    M Garofalo, G Di Leva, G Romano, G Nuovo, … — Cancer Cell, 2009
    … OH). Other 72 cancer and normal (24) lung tissues were purchased from US Biomax, Inc. The human tissues were obtained and studied in strict adherence to …
    SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress
    HS Kim, K Patel, K Muldoon-Jacobs, KS Bisht, … — Cancer Cell, 2010
    … in breast cancer specimens from a commercially available tissue array (US Biomax, Inc.), as compared with normal breast tissue samples ( Figure 7A). In …
    SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity
    HS Kim, A Vassilopoulos, RH Wang, T Lahusen, … — Cancer Cell, 2011
    … Specimens The tissue array of breast cancer samples was purchased from US Biomax (Cat. BR1002). All tissues were collected with the donor being informed …
    The crosstalk of mTOR/S6K1 and Hedgehog pathways
    Y Wang, Q Ding, CJ Yen, W Xia, … — Cancer Cell, 2012
    … at time of enrollment. The multiple tissue microarrays were purchased from US Biomax, Inc. (BC00112 and MTU241; Rockville, MD, …
    Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis
    JH Tsai, JL Donaher, DA Murphy, S Chau, … — Cancer Cell, 2012
    … of 99 human breast carcinoma and matched metastases were purchased from US Biomax Inc. The TMA contained human tissues obtained with informed consent …
    The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas
    Z Xiao, Q Jiang, J Willette-Brown, S Xi, … — Cancer Cell, 2013
    … with their proximal and distal adjacent lung tissues was purchased from US Biomax. The human lung squamous cell carcinoma cell line SW-900 (HTB-59) was …
    CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis
    L Wang, Z Zhao, MB Meyer, S Saha, … — Cancer Cell, 2014
    … breast tumors including lymph node metastasis specimens (C) on the US Biomax BR723
    Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry
    X Feng, MS Degese, R Iglesias-Bartolome, JP Vaque, … — Cancer Cell, 2014
    … Johns Hopkins School of Medicine. Normal skin samples were purchased from US Biomax and …
    PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis
    H Zheng, M Shen, YL Zha, W Li, … — Cancer Cell, 2014
    … PKD1 (pY95-PKD1) and S11-SNAIL in a breast tumor tissue microarray (US Biomax BC081120). χ2 = 10.0, p = 0.0016 by χ2 test. (D) Representative IHC …
    MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
    S Anand, BK Majeti, LM Acevedo, EA Murphy, … — Nat. Med., 2010
    … carcinoma tissue array and normal human tissue array were purchased from US Biomax. In situ hybridization was performed as previously described37 with a …
    Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
    V Barry-Hamilton, R Spangler, D Marshall, S McCauley, … — Nat. Med., 2010
    … Proteogenex, Cooperative Human Tissue Network (Vanderbilt University), US Biomax and University of Massachusetts Cancer Center Tumor Bank. Each …
    A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20
    M Blank, Y Tang, M Yamashita, SS Burkett, … — Nat. Med., 2012
    … with matching normal tissues and the lymphoma tissue array 801 were from US Biomax. Immunohistochemistry of the array was analyzed and quantified by a …
    A versatile genome-scale PCR-based pipeline for high-definition DNA FISH
    M Bienko, N Crosetto, L Teytelman, S Klemm, … — Nat. Methods, 2013
    … control tissue arrays with ten cores were purchased from US …
    Stimulus-dependent phosphorylation of profilin-1 in angiogenesis
    Y Fan, A Arif, Y Gong, J Jia, … — Nat. Cell Biol., 2012
    … from healthy controls or subjects with myocardial infarction (BioChain, US Biomax and BioCat) were de-paraffinized and rehydrated, and subjected to …
    The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis
    K Zhang, CA Corsa, SM Ponik, JL Prior, … — Nat. Cell Biol., 2013
    … microarrays of breast cancer tissues and normal breast tissues were from US Biomax (Rockville). Tissue samples were stained with mouse monoclonal SNAIL1 …
    Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation
    Y Fan, AA Potdar, Y Gong, SM Eswarappa, … — Nat. Cell Biol., 2014
    … specimens from subjects with several tumour types including astrocytoma (US Biomax and BioChain), or healthy controls, were de-paraffinized and rehydrated, …
    Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
    B Ma, Y Chen, L Chen, H Cheng, … — Nat. Cell Biol., 2014
    … breast cancer tissue microarrays were purchased from US Biomax. These tissue microarrays consist of 203–204 analysable cases of invasive breast carcinoma …
    BMP7 Induces Dormancy of Prostatic Tumor Stem Cell in Bone
    A Kobayashi, H Okuda, F Xing, PR Pandey, … — J. Exp. Med., 2011
    … Human Subjects. A prostate cancer tissue microarray was obtained from US Biomax, Inc. The tissue microarray slide contained 41 samples from prostate …
    Unraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migration
    NA Evensen, C Kuscu, HL Nguyen, K Zarrabi, … — J. Natl. Cancer Inst., 2013
    … microarray samples (BR804, BC08013a, and BR10010a) were purchased from US Biomax Inc (Rockville, MD). SNAP Pull-Down Assay and Proteomic Analysis. …
    FBXW7 mutations in melanoma and a new therapeutic paradigm
    IT Aydin, RD Melamed, SJ Adams, M Castillo-Martin, … — J. Natl. Cancer Inst., 2014
    … on formalin-fixed and paraffin-embedded tissue microarray sections (M1004a; US Biomax, Rockville, …
    AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts
    J Zhang, SI Park, MC Artime, JM Summy, … — J. Clin. Invest., 2007
    … tissue arrays. Human prostate tissue arrays were purchased from Cybrdi and US Biomax Inc. Each array spot was 1 mm in diameter and 5 μm in thickness. Two …
    FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2
    T Zuo, R Liu, H Zhang, X Chang, … — J. Clin. Invest., 2007
    … Department of Pathology Tissue Bank, Zymed Laboratories Inc., and US Biomax Inc. Antibodies. Affinity …
    The role of keratinocyte-specific Smad2 loss in skinsquamous cell carcinomas
    KE Hoot, J Lighthall, G Han, SL Lu, … — J. Clin. Invest., 2008
    … skin SCC and normal skin samples were from a human SCC tissue array (US Biomax) and collected from surgically resected specimens between the years 2000 …
    Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation
    B Zheng, JH Jeong, JM Asara, YY Yuan, … — Mol. Cell, 2009
    … Analysis Human melanoma tissue microarray was obtained from US Biomax (Rockville MD). Formalin-fixed paraffin-embedded tissue microarray was …
    The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling
    DS Micalizzi, KL Christensen, P Jedlicka, RD Coletta, … — J. Clin. Invest., 2009
    … Transduction Laboratories), and Smad3 (5 μg/ml; Zymed). Tumor arrays (US Biomax) were stained using Six1 (1:100; Atlas antibodies) and Smad3 (5 μg/ml; …
    Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis
    M Qiao, Y Wang, X Xu, J Lu, … — Mol. Cell, 2010
    … The tissue microarray slides were purchased from US Biomax, Inc (Rockville, MD). Slides were deparaffinized in xylene (thrice for 10 min) …
    Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
    L He, A Ingram, AP Rybak, D Tang, … — J. Clin. Invest., 2010
    … cancer tissue microarray (TMA) slides (US Biomax) contained 5 normal cervical tissues, 5 cancer-adjacent normal cervical tissues SIPL1 …
    Wnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium
    EC Pacheco-Pinedo, AC Durham, KM Stewart, AM Goss, … — J. Clin. Invest., 2011
    … (48 adenocarcinomas) along with normal adult lung tissue (catalog BC041115, US Biomax Inc.) and …
    FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway
    F Kottakis, C Polytarchou, P Foltopoulou, I Sanidas, … — Mol. Cell, 2011
    … a total of 48 cores (40 tumors/eight normal tissues) was purchased from US. Biomax (catalog number BL481). Deidentified lung adenocarcinoma specimens were …
    IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression
    M Liu, DF Lee, CT Chen, CJ Yen, … — Mol. Cell, 2012
    … TNFα-induced IKKα activities are independent of IKKβ. purchased from US Biomax. 2.3 …
    FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice
    SY Lee, R Meier, S Furuta, ME Lenburg, … — J. Clin. Invest., 2012
    … of normal and malignant (stages II and III) tissues were obtained from US Biomax …
    67-kDa laminin receptor increases cGMP to induce cancer-selective apoptosis
    M Kumazoe, K Sugihara, S Tsukamoto, Y Huang, … — J. Clin. Invest., 2013
    … from Amersham Life Sciences. Patient tissue samples were purchased from US Biomax. Samples were incubated overnight at 4°C with the primary …
    Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma
    EL Snyder, H Watanabe, M Magendantz, S Hoersch, … — Mol. Cell, 2013
    … of the Department of Pathology at the Brigham and Women’s Hospital and US Biomax. Studies were carried out in accordance with protocols approved by the …
    Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment
    BA Hanks, A Holtzhausen, KS Evans, R Jamieson, … — J. Clin. Invest., 2013
    … microarrays for human benign nevi and primary and metastatic melanomas (US Biomax Inc., catalog no. ME1003) and both 4T1-sTGFBR3Tet and 66CL4 tumor …
    Epithelial stem cell mutations that promote squamous cell carcinoma metastasis
    RA White, JM Neiman, A Reddi, G Han, … — J. Clin. Invest., 2013
    … to detect miR-9 in tissue arrays of human SCCs and SCC metastases (Biomax). In normal head and neck tissue, miR-9–positive cells were …
    A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity
    P Li, F Du, LW Yuelling, T Lin, … — Nat. Neurosci., 2013
    … to a standard procedure. Human medulloblastoma slides were purchased from US Biomax, …
    Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-β-dependent cancer metastasis
    J Xue, X Lin, WT Chiu, YH Chen, … — J. Clin. Invest., 2014
    … breast primary carcinomas, and matched metastases in lymph nodes (BRM961; US Biomax Inc.) were used in this study. Immunohistochemical analyses were …
    CDK4 deficiency promotes genomic instability and enhances Myc-driven lymphomagenesis
    Y Lu, Y Wu, X Feng, R Shen, … — J. Clin. Invest., 2014
    … lymphoma samples from The Ohio State University Department of Pathology and US Biomax Inc., along with 10 normal LNs, were stained with antibodies specific to …
    Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis
    JB Wu, C Shao, X Li, Q Li, … — J. Clin. Invest., 2014
    … with patient overall survival data, were obtained from Imgenex and US Biomax. Specimens were stained with antibodies specific for MAOA (Santa Cruz), …
    The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer
    ME Diefenbacher, N Popov, SM Blake, C Schülein-Völk, … — J. Clin. Invest., 2014
    … slides containing 70 colon cancer samples and 10 controls were ordered from US Biomax (order no. CO811; http://www.biomax.us/tissue-arrays/Colon/CO811). For …
    Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia
    DH Wang, A Tiwari, ME Kim, NJ Clemons, … — J. Clin. Invest., 2014
    … and esophageal squamous carcinoma from 11 patients was purchased from US Biomax (ES242). These tissue microarrays were submitted for …
    Splicing factor SRSF6 promotes hyperplasia of sensitized skin
    MA Jensen, JE Wilkinson, AR Krainer, , … — Nat. Struct. Mol. Biol., 2014
    … in human tumors was performed with skin-cancer tissue microarrays (US Biomax) as described48. Staining intensities were scored by attributing score …
    The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis
    LE Young, S Sanduja, K Bemis-Standoli, EA Pena, … — Gastroenterology, 2009
    … The colon cancer tissue array CO801 (US Biomax, Rockville, MD) contained 40 tissue cores each of colorectal adenocarcinomas and matched or unmatched …
    KLF4α up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer
    D Wei, L Wang, M Kanai, Z Jia, … — Gastroenterology, 2010
    … higher percentage of KLF4α-positive staining was found in the tissues from US Biomax (Rockville, MD) than that from MD Anderson Cancer Center. …
    Pan-histone deacetylase inhibitor panobinostat sensitizes gastric cancer cells to anthracyclines via induction of CITED2
    I Regel, L Merkl, T Friedrich, E Burgermeister, … — Gastroenterology, 2012
    … array ST843 of gastric cancer was purchased from US Biomax, Inc (Rockville, MD). Animals. (C) Cell survival analysis of pCITED2 and pcDNA3 …
    Enhancer of zeste homolog 2 silences microRNA-218 in human pancreatic ductal adenocarcinoma cells by inducing formation of heterochromatin
    CH Li, KF To, JH Tong, Z Xiao, … — Gastroenterology, 2013
    … tissue microarray consisting of 87 PDAC cases and 10 normal cases (PA2082; US Biomax Inc, Rockville, …
    MIR106B and MIR93 prevent removal of bacteria from epithelial cells by disrupting ATG16L1-mediated autophagy
    C Lu, J Chen, HG Xu, X Zhou, … — Gastroenterology, 2014
    … of the colon were provided by the University Hospital and purchased from US Biomax, Inc (BC05002; Rockville, …
    Autocrine VEGF signaling promotes proliferation of neoplastic Barrett's epithelial cells through a PLC-dependent pathway
    Q Zhang, C Yu, S Peng, H Xu, … — Gastroenterology, 2014
    … esophageal adenocarcinoma tissue arrays purchased from US Biomax (BC0211; Rockville, MD) containing 20 esophageal adenocarcinoma tissues with 20 …
    Activation of EGFR and ERBB2 by Helicobacter pylori results in survival of gastric epithelial cells with DNA damage
    R Chaturvedi, M Asim, MB Piazuelo, F Yan, … — Gastroenterology, 2014
    … The second group consisted of TMAs of gastric tissues purchased from US Biomax, Inc (Rockville, …
    Dickkopf 4 positively regulated by the thyroid hormone receptor suppresses cell invasion in human hepatoma cells
    CH Liao, CT Yeh, YH Huang, SM Wu, … — Hepatology, 2012
    … 40 formalin-fixed liver tissues and 40 hepatocellular carcinoma samples (US Biomax, …
    Receptor for activated C kinase 1 promotes hepatocellular carcinoma growth by enhancing mitogen-activated protein kinase kinase 7 activity
    Y Guo, W Wang, J Wang, J Feng, … — Hepatology, 2013
    … RACK1 (BD Biosciences, San Jose, CA) staining on tissue microarray slides (US Biomax, Inc., Rockville, MD; see …
    MAT2B-GIT1 interplay activates MEK1/ERK 1 and 2 to induce growth in human liver and colon cancer
    H Peng, L Dara, TW Li, Y Zheng, … — Hepatology, 2013
    … 48 colon cancers and their adjacent nontumorous tissues were obtained from US Biomax (Rockville, MD). Written informed consent was obtained from each …
    Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer
    J Wang, L Ma, W Weng, Y Qiao, … — Hepatology, 2013
    … human liver cancer tissue microarray (TMA) slides were purchased from US Biomax (Rockville, MD). Slides …
    Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice
    S Sen, M Langiewicz, H Jumaa, NJ Webster, … — Hepatology, 2014
    … human liver cancer tissue microarray (LV1503) was from US Biomax. H&E-stained sections were scored for inflammation, steatosis, and fibrosis according …
    Connective tissue growth factor and integrin αvβ6: A new pair of regulators critical for ductular reaction and biliary fibrosis
    L Pi, PM Robinson, M Jorgensen, SH Oh, … — Hepatology, 2014
    … were from BioChain (Newark, CA) and human CC tissue arrays were from US Biomax, INC (Rockville, MD). Antibodies used for staining are listed in …
    An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas
    LV Pham, AT Tamayo, C Li, C Bueso-Ramos, … — Blood, 2010
    … 100 cases of LBCL (single core per case; LY1001), were purchased from US Biomax. The tissue …
    Latent KSHV infection increases the vascular permeability of human endothelial cells
    C Guilluy, Z Zhang, PM Bhende, L Sharek, … — Blood, 2011
    … upon VEGF Additionally, normal human skin slides were obtained from US Biomax, …


  1. Ⅰ期非小细胞肺癌中侵袭与转移相关蛋白的表达及其预后意义。 谢泽明,朱志华,张兰军,戎铁华,吴秋良。 中山大学肿瘤防治中心:1 胸科, 2 病理科, 广东 广州 510060。  (link)
  2. Glypican 3 在多种肿瘤中的表达。  (link)
  3. 肝癌组织DNA-PKcs 过量表达及其靶向siRNA 分子的抗增殖作用。 余子建,徐勤枝,周丽君,隋建丽,张士猛,安静,王豫,周平坤。  (link)
  4. 人Bit1 蛋白在淋巴瘤组织中分布的研究。 吴元明,邢小红,王哲,王文勇,黄高昇。 第四军医大学基础部病理学与病理生理学教研室, 陕西 西安 710033。  (link)
  5. 粘着斑激酶在喉及下咽鳞状细胞癌组织芯片中的表达及意义。  (link)
  6. 胃腺癌组织PI3Kp85α、pAkt 及Ki 67表达和意义。 焦学飞。 青岛经济技术开发区第一人民医院普外科。  (link)
  7. 亲环素在非小细胞肺癌中的高表达及其与临床病理特征的关系。 冯艳铭,吴卫东,燕贞,姚武,吴逸明。 第二军医大学学报。 2008年 02期。
    High CyPA expression in non-small cell lung cancer and its relationship with clinical pathological characteristics. FENG Yan-ming, WU Wei-dong, YAN Zhen, YAO Wu, WU Yi-mingDepartment of Occupational Medicine, Institution of Public Health, Zhengzhou University, Zhengzhou 450052, China. Academic Journal of Second Military Medical University. 2008, 02.
  8. HepG2亚群中细胞角蛋白19的表达差异。 周红兵,樊菁,任彦顺,李丙所,党军强,窦科峰。 中国普通外科杂志。 2008年 01期。
    Differential expression of CK19 in subpopulations of HepG2 cell lines. ZHOU Hongbing, FAN Jing, REN Yanshun, LI Bingsuo, DANG Junqiang, DOU Kefeng(Department of Hepatobiliary Surgery; Xijing Hospital; Fourth Military Medical University; Xi′an 710033; China). Chinese Journal of General Surgery. 2008, 01.
  9. MMP-9、LMP-1在鼻NK/T细胞淋巴瘤组织中的表达及意义。 陈曦,徐红,刘月辉,李里香,雷瑛。 实用临床医学。 2008年 01期。
    The Expression and Significance of Matrix Metalloproteinase-9 and Latent Membrane Protein-1 in Nasal NK/T Cell Lymphoma. CHEN Xia, XU Hongb, LIU Yue-huib, LI Li-xiangc, LEI Yingc(a.2005 Grade Department of Medical; Graduate School; b.Department of OtorhinolaryngologyHead and Neck Surgery; the Second Affiliated Hospital; c.Department of Pathology; Nanchang University; Nanchang 330006; China). Practical Clinical Medicine. 2008, 01.
  10. Daxx蛋白在胃癌组织中的表达及意义。 郭丽娟,高艳红,赵治国。 河南医学研究。 2007年 04期。
    Expression of daxx protein and Its significance in gastric carcinoma. GUO Li-juan, GAO Yan-hong, ZHAO Zhi-guo(Department of Digestive Medicine; The Second Affiliated Hospital of Zhengzhou University; Zhengzhou 450014; China). Henan Medical Research. 2007, 04.
  11. 抗白色念珠菌抗体库构建中抗体基因的扩增和克隆。 何文亮,杜孟刚,赵育英,李亚萍,张美萍。 现代检验医学杂志。 2007年 02期。
    Amplification and Clone of Antibody Genes in the Construction of Antibody Library for Candida Albicans. HE Wen-liang, DU Meng-gang, ZHAO Yu-ying, LI Ya-ping, ZHANG Mei-ping(Center of Basic Research; Shaanxi Chao Ying Biotechnology Limited Company; Shaanxi Xi'an 710061; China). Journal of Modern Laboratory Medicine. 2007, 02.
  12. 应用蛋白质组学方法筛选结肠癌相关蛋白质。 裴海平,朱红,曾亮,李宜雄,中南大学湘雅医院普外科,中南大学湘雅医院肿瘤科,湖南省肿瘤医院病理科。 实用肿瘤杂志。 2007年 02期。
    Screening of colon carcinoma associated proteins by proteomics technique. PEI Hai-ping1, ZHU Hong2, ZENG Liang3, et al (1.Department of General Surgery; Xiangya Hospital; Central South University; Changsha; 410008; China; 2.Department of Radiotherapy; 3.Department of Pathology; Hunan Tumor Hospital; 410006; China). Journal of Practical Oncology. 2007. 02.
  13. 组织芯片检测前列腺癌中BRG1表达的研究。 李燕,石群立,金行藻,孟奎,周晓军,孙丽萍。 中华男科学杂志。 2006年 07期。
    BRG1 Expression in Prostate Carcinoma by Application of Tissue Microarray. LI Yan, SHI Qun-li, JIN Xing-zao, MENG Kui, ZHOU Xiao-jun, SUN Li-ping(Department of Pathology, Clinical School of Nanjing University Medical College; Nanjing General Hospital of Nanjing Command; Nanjing; Jiangsu 210002; China). National Journal of Andrology. 2006. 07.
  14. 原位末端标记技术的发展及在临床诊断研究中的应用。 丁秀华,杜孟刚,李军。 中国煤炭工业医学杂志。 2006年 07期。
  15. Cyclin D1在食管癌中的表达及其临床意义。 张旭,黄晓平,马国伟,苏晓东,朱志华,戎铁华。 中山大学学报(医学科学版)。 2006年 06期。
    Cyclin D1 Expression in Esophageal Cancer and Its Clinical Significance. ZHANG Xu, HUANG Xiao-ping, MA Guo-wei, SU Xiao-dong, ZHU Zhi-hua, RONG Tie-hua(State Key Laboratory of South-East Oncology//Department of Thorax; Cancer Center; SUN Yat-sen University; Guangzhou 510060; China). Journal of Sun Yat-Sen University(Medical Sciences). 2006. 06.
  16. 细胞外信号传导激酶在耐药性颞叶癫,患者中的表达。 席志芹,王学峰,吴源,孙纪军,朱曦,肖飞,李劲梅,关立峰,龚云,刘凤英,晏勇,郭珍立,栾国明,张建国,王玉平。 华南肿瘤学国家重点实验室,中山大学肿瘤防治中心胸科。 中山大学学报(医学科学版)。 2006年 06期。
    Overexpression of extracelluar signal regulated protein kinase in the temporal lobe of human drug-resistant epilepsy. XI Zhi-qin, WANG Xue-feng, WU Yuan, SUN Ji-jun, ZHU Xi, XIAO Fei, LI Jin-mei, GUAN Li-feng, GONG Yun, LIU Feng-ying, YAN Yong, GUO Zhen-li, LUAN Guo-ming, ZHANG Jian-guo, WANG Yu-ping (Department of Neurology and the Emphasis Lab of Neurology; the First Affiliated Hospital; Chongqing University of Medical Sciences; Chongqing 400016; China). Journal of Sun Yat-Sen University(Medical Sciences). 2006. 06.
  17. Decorin mRNA和p57~(KIP2) mRNA在非小细胞肺癌中的表达及其临床意义。 戎彪学,蔡曦光,马慧,刘华,董蕙芳,王金穗,兰州大学临床医学院呼吸科,甘肃省人民医院病理科。 临床肿瘤学杂志。 2006年 05期。
    Study on expression of Decorin mRNA and p57~(KIP2) mRNA and their clinical significance in non-small cell lung cancer. RONG Biao-xue, CAI Xi-guang, MA Hui, LIU Hua, DONG Hui-fang, WANG Jin-sui (Department of Pulmonary; Gansu Provincial People's Hospital; Lanzhou 730000; China). Chinese Clinical Oncology. 2006. 05.
  18. p57~(KIP2) mRNA在非小细胞肺癌中的表达及临床意义。 戎彪学,蔡曦光,马慧,刘华,王金穗。 山东医药。 2006年 04期。
  19. DYS1基因在睾丸附睾组织中表达及其微缺失研究。 赵伟,王卫国,马鸣,鹿占鹏。 济宁医学院附属第一人民医院,济宁医学院学报。 2006年 02期。
  20. 组织芯片检测淋巴瘤中活化的细胞毒性细胞。 陈琴,石群立,孟奎,周晓军,吴波,马恒辉,李军,刘镭。 医学研究生学报。 2006年 01期。
    Significance of activated cytotoxic cell in lymphoma by tissue microarray. CHEN Qin, SHI Qun-li, MENG Kui, ZHOU Xiao-jun, WU Bo, MA Heng-hui, LI Jun, LIU Lei(1.Department of Pathology; Nanjing General Hospital of Nanjing Military Command; PLA; Nanjing 210002; Jiangsu; China; 2.Shaanxi ChaoYing Biotechnology Limited company; Xi'an 710061; Shaanxi; China). Journal of Medical Postgraduates. 2006. 01.
  21. chan皮肤鳞癌组织芯片中P53与VEGF表达的关系。 周英芹,於如军,赵海鸥。 南通大学学报(医学版)。 2005年 06期。
    The relationship of the expression of p53 and VEGF in skin squamous cell carcinoma tissue microarray. ZHOU Yingqin, YU Rujun, ZHAO Haiou(Center For Disease and Prevention of Jianhu Country; Jianhu224700; ~1The department of Plastic Surgery; Yancheng First Hospital). Journal of Nantong Medical. 2005. 06.
  22. CacyBP蛋白在胃癌组织中的表达及其临床意义。 王艳,程翌。 华南国防医学杂志。 2005年 05期。
    Expression of CacyBP in Gastric Cancer and Its clinical Significance. WANG Yan, CHENG Yi (Department of Gastroenterology; Wuhan General Hospital; Guangzhou Command; PIA; Wuhan Hubei 430070; China). Military Medical Journal of South China. 2005. 05.
  23. 抗结肠肿瘤相关抗原单克隆抗体的制备及鉴定。 黄海燕,朱勇,刘雪松,蓝天,宋朝君,王鑫,金伯泉,第四军医大学基础部免疫学教研室。 细胞与分子免疫学杂志。 2005年 03期。
  24. β-链接素与基质金属蛋白酶-7在大肠腺瘤及其癌变组织表达的意义。 段光杰,阎晓初,刘丽梅,陈鑫,杜波。 消化外科。 2005年 03期。
    Significance of β-catenin and matrix metalloproteinase-7 expressions in colorectal adenoma and malignant tissue. Duan Guangjie, Yan Xiaoch u, Liu Limei, Chen Xin, Du Bo ( Institute of Pathology Research; Southwest Ho spital; Third Military Medical University; Chongqing 400038). Digestive Surgery. 2005. 03.
  25. 组织微阵列在生物制药研发中的应用。 齐宗利,杜孟刚,李军,霍霞。 国外医学.预防.诊断.治疗用生物制品分册。 2005年 03期。
  26. 原发性肝细胞癌中雌激素受体α与β的表达及临床意义。 宋扬,冯英明,张惠中,闵婕,张贺龙,姬统理,张伟,马宁强。 陕西医学杂志。 2005年 02期。
    Expression of estrogen receptor α and β in hepatocellular carcinoma and clinical significance. Department of Oncology; Tangdu Hospital; the Fourth Military MedicalUniversity (Xi'an 710038) Song Yang Feng Yingming Zhang Huizhong et al. Shaanxi Medical Journal. 2005. 02.
  27. 膀胱癌中缺氧诱导因子和多药耐药相关蛋白表达的组织芯片研究。 邓建华,白进良,傅梧,兰州医学院第一附属医院泌尿外科。 临床泌尿外科杂志。 2004年 09期
    Tissue microarray study of HIF-1α and MRP gene in bladder cancer. DENG Jianhua 1 BAI Jinliang 1 FU Wu 1( 1Department of Urology; the First Affiliated Hospital of Lanzhou Medical College; Lanzhou; Gansu; 730000; China). Journal of Clinical Urology. 2004. 09.
  28. 组织芯片在肿瘤标志物高通量分析中的应用。 李军,张美萍,卫军霞,刘镭。 肿瘤防治杂志。 2004年 08期。
    Tissue microarray technology and its applications with immunohistochemistry. LI Jun, ZHANG Mei-ping, WEI Jun-xia, LIU Lei(Center of Basic Research; Shaanxi Chaoying Biomedicine R & D Limited Company Xi’an 710061; P.R.China). Journal of Qilu Oncology. 2004. 08.
  29. β-链接素和基质金属蛋白酶-7在结直肠腺瘤腺癌组织表达的意义。 段光杰,阎晓初,卞修武,李军,陈鑫。 中华病理学杂志。 2004年 06期。
    The significance of β-catenin and matrix metalloproteinase-7 expression in colorectal adenoma and carcinoma. DUAN Guang jie, YAN Xiao chu, BIAN Xiu wu, LI Jun, CHEN Xin (Institute of Pathology Research; Southwest Hospital; Third Military Medical University; Chongqing 400038; China). Chinese Journal of Pathology. 2004. 06.
  30. 组织芯片技术研究胆囊癌MMP-2和TIMP-2的表达及意义。 ZHU Lin,ZHENG Qi-chang,XIONG Jun,et al.,Department of General Surgery; Union Hospital,Huazhong University of Science and Technology. Wuhan。 腹部外科。 2004年 05期。
  31. 穿孔素与颗粒酶B在鼻NK/T细胞淋巴瘤诊断中的意义。 石群立,周晓军,孟奎,陈琴,盛春宁,李军,陈鑫,刘镭。 临床与实验病理学杂志。 2004年 05期。
    Significance of the expression of perforin and granzyme B in nasal NK/T cell lymphoma. Shi Qunli, Zhou Xiaojun, Meng Kui, Chen Qin, Sheng Chunning, Li Jun, Chen Xin, Liu Lei(Department of Pathology; Nanjing Military General Hospital of PLA; Nanjing 210002). Chinese Journal of Clinical and Experimental Pathology. 2004. 05.
  32. 一种新的非病毒基因转移载体及其体外细胞转染活性研究。 刘永军,李亚萍,李军,刘镭。 生物技术。 2004年 04期。
    Study on A Novel Non-viral Vector for DNA Delivery and Its Transfection Activity in the Cultured Cell. LIU Yong-jun, LI Ya-ping, LI Jun, LIU Le(1.Center of the Basic Research; Shanxi ChaoYing Biomedicine R&D Limited Company; Xi'an 710061; 2.Shanxi Province Key Laboratory of Biotechnology; North-west University; Xi'an 710069; P.R.China). Biotechnology. 2004. 04.
  33. 抗凋亡蛋白BAG-1在胃癌组织芯片中的表达及意义。 师建国,王丽,张勇,闫庆国,第四军医大学病理学教研室。 细胞与分子免疫学杂志。 2004年 04期。
  34. 组织芯片制备与原位分析技术。 李军,步雪,杜波,张美萍,李小华,刘镭。 中国实验诊断学。 2004年 03期。
    Preparation of tissue array and applications of in situ analysis technology. LI Jun; BU Xue; DU Bo; et al(The center of basic study; Shaanxi Chaoying Bio-science and technology Ltd). Chinese Journal of Laboratory Diagnosis. 2004 03.
  35. 组织芯片检测乳腺癌中E-cadherin表达的研究。 石群立,周晓军,孟奎,马捷,陈琴,吴波,陆珍凤,盛春宁,李军,刘镭,南京军区南京总医院病理科,陕西超英生物医学研究开发有限公司。 医学研究生学报。 2004年 02期。
    E-cadherin expression in breast carcinoma by the application of tissue microarray. SHI Qun-li, ZHOU Xiao-jun, MENG kui, MA Jie, CHEN Qin, WU Bo, LU Zhen-feng, SHENG Chun-ning, LI Jun, LIU Lei (1.Department of Pathology; Nanjing General Hospital of Nanjing Command; Nanjing 210002; Jiangsu; China; 2.CYBRDI; Xi'an 710061; Shaanxi; China). Journal of Medical Postgraduates. 2004. 02.
  36. 组织芯片检测乳腺癌相关癌基因产物表达。 石群立,孟奎,周晓军,陈琴,吴波,马恒辉,陆珍凤,盛春宁,李军,陈鑫,刘镭,南京军区南京总医院病理科,陕西超英生物医学研究开发有限公司。 临床与实验病理学杂志。 2003年 03期。
    Evaluate the expression of associated genes production in breast carcinoma by the application of tissue microarray. Shi Qunli, Meng Kui, Zhou Xiaojun, Chen Qin, Wu Bo, Ma Henghui, Lu Zhenfeng, Sheng Chunning, Li Jun, Chen Xin, Liu Lei(Department of Pathology; General Hospital of Nanjing Military Area; Nanjing 210002). Chinese Journal of Clinical and Experimental Pathology. 2003. 03.
  37. 用组织芯片研究结直肠腺癌组织中nm23mRNA,CD44s和CD44v6的表达意义。 刘永军,李军,晏培松,王学民,陈鑫,李德全,刘文康,贾敬芬,刘镭。 第四军医大学学报。 2002年18期。
    Study on the expression and significance of nm23 mRNA, CD44s and CD44v6 in human colorectal adenocarcinoma by tissue microarray. LIU Yong-Jun, LI Jun, YAN Pei-Song, WANG Xue-Ming, CHEN Xin, LI De-Quan, LIU Wen-Kang, JIA Jing-Fen 3, LIU Lei (Basic Research Center; Shaanxi Chaoying Biomedicine (R&D) Ltd; Xi'an 710061; China; 2Department of Pathology). Journal of The Fourth Military Medical University. 2002. 18.
  38. 结直肠腺癌组织中nm23-H1和MDR-1mRNA表达及与其临床病理因素的关系。 李军,刘文康,陈鑫,李德全,杜波,刘镭。 实用癌症杂志。 2002年 06期。
    Expressions of nm23-H1 and MDR-1 in Colorectal Tissues Associate with Invasion and Metastasis of Colorectal Adenocarcinoma. LI Jun, LIU Wen kang, CHEN Xin, et al. (Research Center of Cancer; Chaoying Biomedicine R&D Co.Ltd; Xian; 710061). The Practical Journal of Cancer. 2002. 06.
  39. 组织芯片的制备技术。 王学民,李军,杜波,陈鑫,李德全,刘文康,刘镭。 诊断病理学杂志。 2002年 06期。
  40. 组织芯片技术与肿瘤研究。 李军,刘镭综述,王一理审校。 肿瘤学杂志。 2002年。
  41. 1.人源肝癌单链抗体的表达及功能研究 2.COX-2在肝癌诱导肿瘤新生血管形成中作用机制研究。 赵清涛。 第四军医大学。
    1.Expression of Human Single-chain Antibody Against Hepatocellular Cancer, and the Function Study of the Scfv Protein 2. Potential Involvement of the Cyclooxygenase-2 Pathway in Hepatocellular Carcinoma-associated Angiogenesis. ZHAO Qingtao. The Fourth Military Medical University.
  42. 环境内毒素应答新分子的表达分析及对HEK293细胞生长及周期的影响。
    Expression Analysis of Environmental Endotoxin Responsive New Molecular and Effection of Its on Proliferation and Cell Cycle in HEK293 Cells.

用原陕西超英生物科技公司(Cybrdi, Shanxi ChaoYing Biotechnology Co., LTD)生产的Cybrdi组织芯片发表的部分英文参考文献

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